Endometrial stem/progenitor cells

Human endometrium regenerates and regresses with each menstrual cycle under hormonal control throughout a woman's reproductive life. The cyclical regeneration and remodeling potentials allude to the existence of stem/progenitor cells in the endometrium. There is increasing evidence that human e...

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Bibliographic Details
Published in:The journal of obstetrics and gynaecology research 2014-09, Vol.40 (9), p.2015-2022
Main Author: Maruyama, Tetsuo
Format: Article
Language:English
Subjects:
Adult
Adult Stem Cells - cytology
Adult Stem Cells - pathology
Animals
Cell Movement
endometrial regeneration
endometriosis
Endometriosis - pathology
Endometrium - cytology
Endometrium - pathology
Female
Humans
Menstrual Cycle
Models, Biological
side population
stem/progenitor cells
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Summary:Human endometrium regenerates and regresses with each menstrual cycle under hormonal control throughout a woman's reproductive life. The cyclical regeneration and remodeling potentials allude to the existence of stem/progenitor cells in the endometrium. There is increasing evidence that human endometrium contains small numbers of stem‐like cells capable of self‐renewal, multiple differentiation and tissue reconstitution. Although the precise identity of endometrial stem/progenitor cells remains elusive, these cells are thought to play pivotal role(s) in the physiological remodeling and regeneration of the human endometrium and also in the pathogenesis of endometrium‐associated diseases, such as endometriosis.
ISSN:1341-8076
1447-0756
DOI:10.1111/jog.12501