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Efficacy and tolerability of luliconazole cream 1% for dermatophytoses: A Meta-analysis

We evaluated the efficacy and safety of luliconazole cream 1% in the treatment of dermatophytoses. According to our meta‐analysis, short‐term treatment of luliconazole cream 1% can result in the complete clearance of dermatophytoses. It showed that 1% luliconazole was more effective than controlled...

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Bibliographic Details
Published in:Journal of dermatology 2014-09, Vol.41 (9), p.779-782
Main Authors: Feng, Xiaowei, Xie, Jinwei, Zhuang, Kaiwen, Ran, Yuping
Format: Article
Language:English
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Summary:We evaluated the efficacy and safety of luliconazole cream 1% in the treatment of dermatophytoses. According to our meta‐analysis, short‐term treatment of luliconazole cream 1% can result in the complete clearance of dermatophytoses. It showed that 1% luliconazole was more effective than controlled drugs or vehicle (week 4: odds ratio = 1.46, 95% confidence interval = 1.12–1.91), and no more adverse events occurred in the 1% luliconazole group (week 4: odds ratio = 1.01, 95% confidence interval = 0.71–1.44). This effect strengthens the evidence for luliconazole cream 1% being more effective than vehicle, 1% terbinafine, 1% bifonazole, and 0.1% or 0.5% luliconazole.
ISSN:0385-2407
1346-8138
DOI:10.1111/1346-8138.12577