ESHRE Task Force on Ethics and Law 21: genetic screening of gamete donors: ethical issues

This Task Force document explores the ethical issues involved in the debate about the scope of genetic screening of gamete donors. Calls for expanded donor screening arise against the background of both occasional findings of serious but rare genetic conditions in donors or donor offspring that were...

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Bibliographic Details
Published in:Human reproduction (Oxford) 2014-07, Vol.29 (7), p.1353-1359
Main Authors: Dondorp, W, De Wert, G, Pennings, G, Shenfield, F, Devroey, P, Tarlatzis, B, Barri, P, Diedrich, K, Eichenlaub-Ritter, U, Tüttelmann, F, Provoost, V
Format: Article
Language:English
Subjects:
Advisory Committees
Ethics, Medical
Europe
Female
Genetic Testing
Guidelines as Topic
Heterozygote
Humans
Informed Consent
Insemination, Artificial, Heterologous - ethics
Insemination, Artificial, Heterologous - legislation & jurisprudence
Male
Oocyte Donation - ethics
Oocyte Donation - legislation & jurisprudence
Patient Safety
Risk
Tissue Donors - ethics
Tissue Donors - legislation & jurisprudence
United States
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Summary:This Task Force document explores the ethical issues involved in the debate about the scope of genetic screening of gamete donors. Calls for expanded donor screening arise against the background of both occasional findings of serious but rare genetic conditions in donors or donor offspring that were not detected through present screening procedures and the advent of new genomic technologies promising affordable testing of donors for a wide range of conditions. Ethical principles require that all stakeholders' interests are taken into account, including those of candidate donors. The message of the profession should be that avoiding all risks is impossible and that testing should remain proportional.
ISSN:0268-1161
1460-2350
DOI:10.1093/humrep/deu111