Histological analysis of the periodontal ligament and alveolar bone during dental movement in diabetic rats subjected to low-level laser therapy

• Published in: Journal of photochemistry and photobiology. B, Biology Biology, 2014-06, Vol.135, p.65-74
• Main Authors: Maia, Luiz Guilherme Martins, Alves, Angela Valéria Farias, Bastos, Talita Santos, Moromizato, Lucas Sandes, Lima-Verde, Isabel Bezerra, Ribeiro, Maria Amália Gonzaga, Gandini Júnior, Luiz Gonzaga, de Albuquerque-Júnior, Ricardo Luiz Cavalcanti
• Format: Article
• Language: English
• Subjects: Alveolar Process - metabolism; Alveolar Process - pathology; Alveolar Process - radiation effects; Animals; Blood Vessels - radiation effects; Cell Count; Collagen - metabolism; Diabetes Mellitus, Experimental - pathology; Diabetes Mellitus, Experimental - radiotherapy; Low-Level Light Therapy - adverse effects; Male; Osteoblasts - pathology; Osteoblasts - radiation effects; Osteoclasts - pathology; Osteoclasts - radiation effects; Periodontal Ligament - metabolism; Periodontal Ligament - pathology; Periodontal Ligament - radiation effects; Rats; Rats, Wistar; Tooth Movement Techniques
• ISSN: 1011-1344; 1873-2682
• DOI: 10.1016/j.jphotobiol.2014.03.023

The purpose of this research was to evaluate the histological changes of the periodontal ligament and alveolar bone during dental movement in diabetic rats subjected to low level laser therapy (LLLT). The movement of the upper molar was performed in 60 male Wistar rats divided into four groups (n=15): CTR (control), DBT (diabetic), CTR/LT (irradiated control) and DBT/LT (irradiated diabetic). Diabetes was induced with alloxan (150 mg/kg, i.p.). LLLT was applied with GaAlAs laser at 780 nm (35 J/cm(2)). After 7, 13 and 19 days, the periodontal ligament and alveolar bone were histologically analyzed. The mean of osteoblasts (p