Fecal microbiota transplantation in treating Clostridium difficile infection

Clostridium difficile infection (CDI) is an increasingly common and severe international health problem. Customary treatment of this infection, usually with antibiotics, is often ineffective and its recurrence is common. In recent years the treatment of recurrent or refractory CDI by the transfer of...

Full description

Saved in:
Bibliographic Details
Published in:Journal of digestive diseases 2014-08, Vol.15 (8), p.405-408
Main Author: Brown, William R
Format: Article
Language:English
Subjects:
Clostridium difficile
dysbiosis
Enterocolitis, Pseudomembranous - microbiology
Enterocolitis, Pseudomembranous - therapy
fecal enema
fecal microbiota transplantation
Feces
Feces - microbiology
Humans
Infections
Microbiota
Patient Acceptance of Health Care
pseudomembranous enterocolitis
Tissue Transplantation - adverse effects
Tissue Transplantation - methods
Tissue Transplantation - trends
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Clostridium difficile infection (CDI) is an increasingly common and severe international health problem. Customary treatment of this infection, usually with antibiotics, is often ineffective and its recurrence is common. In recent years the treatment of recurrent or refractory CDI by the transfer of stool from an uninfected person, so called fecal “microbiota transplantation” has become recognized as effective and generally safe. The effectiveness of this novel treatment is incompletely defined but is likely to be due to its correction of the intestinal dysbiosis that characterizes the disease. Practical methods for the administration of the transplantation have been described. This review summarizes the current reported experiences with fecal microbiota transplantation in the treatment for CDI.
ISSN:1751-2972
1751-2980
DOI:10.1111/1751-2980.12160