Salmonella T3SSs: successful mission of the secret(ion) agents

Highlights ► This text reviews the most recent discoveries on the structure, regulation of expression and activity of Salmonella type three secretion systems. ► The dichotomy of T3SSs functions is not as clear-cut as anticipated. ► The regulation of both type three secretion systems is partly inter-...

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Bibliographic Details
Published in:Current opinion in microbiology 2013-02, Vol.16 (1), p.38-44
Main Authors: Moest, Thomas P, Méresse, Stéphane
Format: Article
Language:English
Subjects:
Animals
bacteria
bacterial proteins
Bacterial Proteins - metabolism
Bacterial Secretion Systems
Gene Expression Regulation, Bacterial
Humans
inflammation
organelles
Pathology
Protein Transport
Salmonella
Salmonella - genetics
Salmonella - metabolism
Salmonella - pathogenicity
secretion
Virulence Factors - metabolism
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Summary:Highlights ► This text reviews the most recent discoveries on the structure, regulation of expression and activity of Salmonella type three secretion systems. ► The dichotomy of T3SSs functions is not as clear-cut as anticipated. ► The regulation of both type three secretion systems is partly inter-dependent, with fine-tuning by differential and cross-talking pathways. ► The diverging patterns of expression and activity of T3SSs may advance the chances of Salmonella to outpace competitors.
ISSN:1369-5274
1879-0364
DOI:10.1016/j.mib.2012.11.006