Development of immunization trials against Pasteurella multocida

Highlights • Pasteurellosis is a major respiratory disease for important farm animals caused by Pasteurella multocida. • Chemotherapeutic treatment is expensive, lengthy, and ineffective. • Biosecurity precautions may share to diminish the widespread of the pathogen, but cannot control it. • Almost...

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Bibliographic Details
Published in:Vaccine 2014-02, Vol.32 (8), p.909-917
Main Authors: Ahmad, Tarek A, Rammah, Samar S, Sheweita, Salah A, Haroun, Medhat, El-Sayed, Laila H
Format: Article
Language:English
Subjects:
Allergy and Immunology
Animals
Antibiotics
Applied microbiology
Bacterial Vaccines - therapeutic use
Bacteriology
Biological and medical sciences
Clinical Trials as Topic - veterinary
Fundamental and applied biological sciences. Psychology
Immunization
Immunotherapy
Infections
Livestock
Microbiology
Miscellaneous
Mortality
Pasteurella
Pasteurella Infections - prevention & control
Pasteurella Infections - veterinary
Pasteurella multocida
Pasteurellosis
Pathogens
Poultry
Respiratory diseases
Vaccine
Vaccines
Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)
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Summary:Highlights • Pasteurellosis is a major respiratory disease for important farm animals caused by Pasteurella multocida. • Chemotherapeutic treatment is expensive, lengthy, and ineffective. • Biosecurity precautions may share to diminish the widespread of the pathogen, but cannot control it. • Almost all types of vaccines were constructed to prevent the pathogen, but none was fully successful. • A new regimen depending on both killed and live attenuated vaccination demonstrated full potency.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2013.11.068