Tubular dysfunction in HIV-infected patients on antiretroviral therapy in an HIV clinic in Mexico

The objective of this study is to investigate whether HIV-infected patients using tenofovir-based regimen are at increased risk of tubular dysfunction. We conducted an observational, comparative, longitudinal, prospective study, in HIV treatment-naive infected patients who had indication to start tr...

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Bibliographic Details
Published in:Antiviral therapy 2013-01, Vol.18, p.A81-A81
Main Authors: Andrade-Fuentes, K, Manjarrez-Tellez, B, Gaytan-Martinez, J, Vazquez-Vega, G, Garcia-Yanez, J C, Ramirez, J L Sandoval, Mata-Marin, J A
Format: Article
Language:English
Subjects:
Human immunodeficiency virus
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Summary:The objective of this study is to investigate whether HIV-infected patients using tenofovir-based regimen are at increased risk of tubular dysfunction. We conducted an observational, comparative, longitudinal, prospective study, in HIV treatment-naive infected patients who had indication to start treatment. Regarding backbone, we started with tenofovir/emtricitabine or abacavir/lamivudine. Tubular dysfunction is common in HIVinfected patients on antiretroviral therapy, TDF-based regimen is associated with decrease in eGFR and tubular dysfunction but it was not statistically significant. Patients on antiretroviral therapy require complete and periodical renal function assessment.
ISSN:1359-6535