Bisphosphonate-induced Osteonecrosis of the Maxilla Presenting as a Cicatricial Ectropion

Abstract Case Report: A 63-year-old gentleman, who was being treated with bisphosphonates for multiple myeloma, presented with a cicatricial ectropion of the lower eyelid, without exposure keratopathy. A CT scan demonstrated extensive destruction of bone with an infraorbital fracture surrounded by s...

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Bibliographic Details
Published in:Orbit (Amsterdam) 2014-10, Vol.33 (5), p.369-371
Main Authors: Malik, Rizwan, Fernando, Bertie S., Laitt, Roger D., Leatherbarrow, Brian
Format: Article
Language:English
Subjects:
Bone Density Conservation Agents - adverse effects
Diphosphonates - adverse effects
Ectropion - chemically induced
Ectropion - diagnosis
Eyelids - pathology
Humans
Male
Maxillary Diseases - chemically induced
Maxillary Diseases - diagnostic imaging
Middle Aged
Multiple Myeloma - drug therapy
Osteonecrosis - chemically induced
Osteonecrosis - diagnostic imaging
Tomography, X-Ray Computed
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Summary:Abstract Case Report: A 63-year-old gentleman, who was being treated with bisphosphonates for multiple myeloma, presented with a cicatricial ectropion of the lower eyelid, without exposure keratopathy. A CT scan demonstrated extensive destruction of bone with an infraorbital fracture surrounded by sclerotic bony changes. The patient was managed conservatively with discontinuation of bisphosphonate therapy and topical ocular lubricants. The patient's condition remained unchanged a year after this initial management.
ISSN:0167-6830
1744-5108
DOI:10.3109/01676830.2013.814683