Modification of Abdominal Fat Distribution After Aromatase Inhibitor Therapy in Breast Cancer Patients Visualized Using 3-D Computed Tomography Volumetry

Micro-Abstract The pattern of abdominal fat distribution is hormone linked and it can affect or be predictive of various diseases, in particular metabolic syndrome is associated with an increase amount of visceral adipose tissue. After system therapy with aromatase inhibitor in breast cancer patient...

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Bibliographic Details
Published in:Clinical breast cancer 2014-10, Vol.14 (5), p.365-370
Main Authors: Battisti, Sofia, Guida, Francesco Maria, Coppa, Federica, Vaccaro, Donata M, Santini, Daniele, Tonini, Giuseppe, Zobel, Bruno B, Semelka, Richard C
Format: Article
Language:English
Subjects:
Aromatase inhibitor therapy
Aromatase Inhibitors - adverse effects
Body Fat Distribution
Breast cancer
Breast Neoplasms - drug therapy
Female
Hematology, Oncology and Palliative Medicine
Humans
Imaging, Three-Dimensional
Intra-Abdominal Fat - diagnostic imaging
Intra-Abdominal Fat - drug effects
Middle Aged
Obstetrics and Gynecology
Subcutaneous fat
Subcutaneous Fat - diagnostic imaging
Subcutaneous Fat - drug effects
Tomography, X-Ray Computed
Visceral fat
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Summary:Micro-Abstract The pattern of abdominal fat distribution is hormone linked and it can affect or be predictive of various diseases, in particular metabolic syndrome is associated with an increase amount of visceral adipose tissue. After system therapy with aromatase inhibitor in breast cancer patients, we found a relative increase of visceral adipose tissue regardless of whether they gained or lost weight after therapy.
ISSN:1526-8209
1938-0666
DOI:10.1016/j.clbc.2014.02.003