Profiling of substrate-specificity and rational design of broad-spectrum peptidomimetic inhibitors for main proteases of coronaviruses

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Bibliographic Details
Published in:Hong Kong medical journal = Xianggang yi xue za zhi 2014-08, Vol.20 Suppl 4, p.22-25
Main Authors: Chuck, C P, Ke, Z H, Chen, C, Wan, D C C, Chow, H F, Wong, K B
Format: Article
Language:English
Subjects:
Amino Acids
Cysteine Endopeptidases - chemistry
Drug Design
Inhibitory Concentration 50
Molecular Structure
Oligopeptides - chemical synthesis
Peptidomimetics - chemical synthesis
Protease Inhibitors - chemical synthesis
SARS Virus - classification
SARS Virus - enzymology
Substrate Specificity
Viral Proteins - antagonists & inhibitors
Viral Proteins - chemistry
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ISSN:1024-2708