Risk factors for ventilator-associated pneumonia in neonatal intensive care unit patients

Abstract Ventilator-associated pneumonia (VAP) is a serious complication in neonatal patients on mechanical ventilation. The objective of this study was to examine the incidence and risk factors associated with VAP, particularly in every 7-day versus every 14-day ventilator circuit changes, in a neo...

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Bibliographic Details
Published in:Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 2014-10, Vol.20 (10), p.627-630
Main Authors: Kawanishi, Fumiko, Yoshinaga, Masami, Morita, Michiyo, Shibata, Yuriko, Yamada, Tomoyuki, Ooi, Yukimasa, Ukimura, Akira
Format: Article
Language:English
Subjects:
Birth Weight
Female
Gestational Age
Hematology, Oncology and Palliative Medicine
Humans
Incidence
Infant, Newborn
Intensive Care Units, Neonatal
Intubation, Intratracheal - statistics & numerical data
Male
Neonatal intensive care unit (NICU)
Pneumonia, Ventilator-Associated - epidemiology
Respiration, Artificial - methods
Retrospective Studies
Risk Factors
Time Factors
Ventilator circuit
Ventilator-associated pneumonia (VAP)
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Summary:Abstract Ventilator-associated pneumonia (VAP) is a serious complication in neonatal patients on mechanical ventilation. The objective of this study was to examine the incidence and risk factors associated with VAP, particularly in every 7-day versus every 14-day ventilator circuit changes, in a neonatal intensive care unit (NICU). Seventy-one neonates hospitalized in the NICU were enrolled. First, the neonates were divided into groups with and without VAP. On univariate logistic regression analyses, prolonged mechanical ventilation, frequent re-intubation, low gestational age, and low birth weight (BW) were significant risk factors for VAP development. After adjustments for other variables, only BW
ISSN:1341-321X
1437-7780
DOI:10.1016/j.jiac.2014.06.006