Long-Term Follow-Up Results of the Observation Program for Neuroblastoma Detected at 6-Month Mass Screening

We conducted an observation program of neuroblastoma in infants, detected by mass screening at 6 months of age; we followed up with them for 15 years. No recurrence was observed after disappearance of tumors, and persistent tumors showed no malignant transformation or metastasis. Histology of the re...

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Bibliographic Details
Published in:The Journal of pediatrics 2014-10, Vol.165 (4), p.855-857.e1
Main Authors: Arakawa, Ayumu, MD, Oguma, Eiji, MD, Aihara, Toshinori, MD, Kishimoto, Hiroshi, MD, Kikuchi, Akira, MD, Hanada, Ryoji, MD, Koh, Katsuyoshi, MD
Format: Article
Language:English
Subjects:
Adrenal Gland Neoplasms - physiopathology
Adrenal Gland Neoplasms - therapy
Age Factors
Child, Preschool
Female
Follow-Up Studies
Ganglioneuroblastoma - physiopathology
Ganglioneuroblastoma - therapy
Ganglioneuroma - physiopathology
Ganglioneuroma - therapy
Homovanillic Acid - urine
Humans
Infant
Magnetic Resonance Imaging
Male
Mass Screening
Neuroblastoma - physiopathology
Neuroblastoma - therapy
Pediatrics
Recurrence
Retroperitoneal Neoplasms - physiopathology
Retroperitoneal Neoplasms - therapy
Treatment Outcome
Vanilmandelic Acid - urine
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Summary:We conducted an observation program of neuroblastoma in infants, detected by mass screening at 6 months of age; we followed up with them for 15 years. No recurrence was observed after disappearance of tumors, and persistent tumors showed no malignant transformation or metastasis. Histology of the resected tumors showed age-related differentiation.
ISSN:0022-3476
1097-6833
DOI:10.1016/j.jpeds.2014.06.055