Two cases of Creutzfeldt-Jakob disease from an ongoing dementia registry in Pakistan

Creutzfeldt-Jakob disease (CJD) is a rare prion disease that leads to a rapidly progressive dementia (RPD) and associated neurological features. It is not well documented in our country; therefore its true prevalence in Pakistan is not known. Here we report two cases of sporadic probable CJD seen in...

Full description

Saved in:
Bibliographic Details
Published in:Journal of the Pakistan Medical Association 2014-06, Vol.64 (6), p.705-707
Main Authors: Ahmad, Arsalan, Rao, Faiza, Aieshah, Sahrish
Format: Article
Language:English
Subjects:
Aged
Creutzfeldt-Jakob disease
Creutzfeldt-Jakob Syndrome - diagnosis
Creutzfeldt-Jakob Syndrome - epidemiology
Dementia
Diagnosis
Diagnosis, Differential
Diffusion Magnetic Resonance Imaging
Electroencephalography
Female
Humans
Middle Aged
Pakistan - epidemiology
Registries
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Creutzfeldt-Jakob disease (CJD) is a rare prion disease that leads to a rapidly progressive dementia (RPD) and associated neurological features. It is not well documented in our country; therefore its true prevalence in Pakistan is not known. Here we report two cases of sporadic probable CJD seen in our hospital. The first, a 62 years old female, presented with RPD and myoclonus. The second was a 72 years old female who presented with generalized axial and limb rigidity, mutisim, personality changes and hallucinations along with RPD. Both cases were diagnosed as CJD on the basis of clinical, MRI and EEG findings.
ISSN:0030-9982