Vitamin D status in 6- to 10-year-old children: a French multicenter study in 326 children

• Published in: Archives de pédiatrie : organe officiel de la Société française de pédiatrie 2014-10, Vol.21 (10), p.1106-1114
• Main Authors: Mallet, E, Gaudelus, J, Reinert, P, Stagnara, J, Bénichou, J, Basuyau, J-P, Maurin, M, Cordero, J, Roden, A, Uhlrich, J
• Format: Article
• Language: fre
• Subjects: Calcium, Dietary - administration & dosage; Child; Female; France - epidemiology; Humans; Male; Seasons; Sunlight; Vitamin D - administration & dosage; Vitamin D - blood; Vitamin D Deficiency - diagnosis; Vitamin D Deficiency - epidemiology; Vitamins - administration & dosage
• ISSN: 1769-664X
• DOI: 10.1016/j.arcped.2014.04.012

To assess the vitamin D status of children aged 6-10years in the French general population for whom no guidelines have yet been defined due to insufficient data. The study was conducted during two winters with very different sunshine levels: 5 March to 17 April 2012 and 8 January to 16 April 2013 in 20 then 22 centers. Three hundred children (60 children for each year of age) attending an ambulatory care unit or outpatient department for a reason unrelated to vitamin D status were included at the end of winter in 20 hospital centers (ten centers in the northern half of France above latitude 46-47°N/Lille: 50°N and ten centers in the southern half of France below latitude 46-47°N/Marseille: 43°N). Centralized 25 hydroxyvitamin D (25(OH)D), alkaline phosphatase (ALP), and parathormone (PTH) assays were performed on leftover blood samples. The currently accepted normal range for 25(OH)D was used to define the following categories: ≤25nmol/L: severe vitamin D deficiency, 25nmol/L