Chronic adipose tissue inflammation: all immune cells on the stage

Highlights • Different immune cells in visceral adipose tissue are actively involved in inflammatory processes during obesity. • Their recruitment to adipose tissue and distinct cytokine profile is a hallmark of obesity/type 2 diabetes and can be targeted for therapeutic purposes.

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Bibliographic Details
Published in:Trends in molecular medicine 2013-08, Vol.19 (8), p.487-500
Main Authors: Cildir, Gökhan, Akıncılar, Semih Can, Tergaonkar, Vinay
Format: Article
Language:English
Subjects:
Adipose Tissue - immunology
Animals
Chronic Disease
Humans
Immune System - cytology
Immune System - immunology
Obesity - immunology
Pathology
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Description
Summary:Highlights • Different immune cells in visceral adipose tissue are actively involved in inflammatory processes during obesity. • Their recruitment to adipose tissue and distinct cytokine profile is a hallmark of obesity/type 2 diabetes and can be targeted for therapeutic purposes.
ISSN:1471-4914
1471-499X
DOI:10.1016/j.molmed.2013.05.001