Osseous regeneration after therapy in patients with head and neck tumors

• Published in: Cancer 1989-09, Vol.64 (6), p.1222-1225
• Main Authors: Estrin, E., Kelly, J., Lazo, A., Al‐Katib, A., Al‐Sarraf, M.
• Format: Article
• Language: English
• Subjects: Adult; Aged; Biological and medical sciences; Carcinoma, Squamous Cell - diagnostic imaging; Carcinoma, Squamous Cell - physiopathology; Carcinoma, Squamous Cell - therapy; Combined Modality Therapy; Humans; Lymphoma, Non-Hodgkin - diagnostic imaging; Lymphoma, Non-Hodgkin - physiopathology; Lymphoma, Non-Hodgkin - therapy; Male; Maxillary Sinus Neoplasms - diagnostic imaging; Maxillary Sinus Neoplasms - physiopathology; Maxillary Sinus Neoplasms - therapy; Medical sciences; Middle Aged; Nasopharyngeal Neoplasms - diagnostic imaging; Nasopharyngeal Neoplasms - physiopathology; Nasopharyngeal Neoplasms - therapy; Osteogenesis; Otorhinolaryngology (head neck, general aspects and miscellaneous); Otorhinolaryngology. Stomatology; Paranasal Sinus Neoplasms - diagnostic imaging; Tomography, X-Ray Computed; Tumors
• ISSN: 0008-543X; 1097-0142
• DOI: 10.1002/1097-0142(19890915)64:6<1222::AID-CNCR2820640610>3.0.CO;2-0

Four patients with head and neck tumors were observed by serial computed tomography (CT) during treatment. Osseous regeneration was demonstrated at sites of initial osteolytic destruction in two patients who responded to therapy. This regeneration was observed at 4 and 7 months, respectively, after the start of therapy. No such regeneration could be seen in the other two patients who did not respond to treatment. CT may be useful not only in demonstrating initial osseous invasion, but also in monitoring treatment response.