Anticoagulant activity of a proteoglycan in extracts of Codium fragile ssp. atlanticum

Aqueous extracts of Codium fragile ssp. atlanticum possess marked anticoagulant activity. The compounds responsible appear to be proteoglycans with molecular weights, determined by a low angle, laser light-scattering method, of 1.8 x 10 super(6) daltons, with a polydispersity value of 1.2.

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Bibliographic Details
Published in:Journal of applied phycology 1990-12, Vol.2 (4), p.357-361
Main Authors: Rogers, D J, Jurd, K M, Blunden, G, Paoletti, S, Zanetti, F
Format: Article
Language:English
Subjects:
anticoagulants
aquatic drugs
blood
Codium fragile atlanticum
Marine
metabolites
pharmacology
proteoglycans
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Description
Summary:Aqueous extracts of Codium fragile ssp. atlanticum possess marked anticoagulant activity. The compounds responsible appear to be proteoglycans with molecular weights, determined by a low angle, laser light-scattering method, of 1.8 x 10 super(6) daltons, with a polydispersity value of 1.2.
ISSN:0921-8971
DOI:10.1007/BF02180926