The enhancing effect of fucoidan derived from Undaria pinnatifida on immunoglobulin production by mouse spleen lymphocytes

In this study, we revealed that a Mekabu (Udaria pinnantifida) extract enhanced immunoglobulin (Ig) production of mouse spleen lymphocytes. Furthermore, it was suggested that water-soluble and high molecular weight ingredients in the Mekabu extract have significant enhancing effect on Ig production....

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Bibliographic Details
Published in:Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2014-10, Vol.78 (10), p.1743-1747
Main Authors: Takai, Mika, Miyazaki, Yoshiyuki, Tachibana, Hirofumi, Yamada, Koji
Format: Article
Language:English
Subjects:
Animals
Female
fucoidan
immunoglobulin (Ig)
Immunoglobulins - biosynthesis
Lymphocytes - drug effects
Lymphocytes - metabolism
Mekabu (Undaria pinnatifida)
Mice
Molecular Weight
mouse spleen lymphocytes
Polysaccharides - chemistry
Polysaccharides - pharmacology
Spleen - immunology
Undaria - chemistry
water extract
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Summary:In this study, we revealed that a Mekabu (Udaria pinnantifida) extract enhanced immunoglobulin (Ig) production of mouse spleen lymphocytes. Furthermore, it was suggested that water-soluble and high molecular weight ingredients in the Mekabu extract have significant enhancing effect on Ig production. Therefore, fucoidan was estimated as the active component.
ISSN:0916-8451
1347-6947
DOI:10.1080/09168451.2014.930323