Muscarinic receptor binding and activation of second messengers by substituted N-methyl-N-(4-(1-azacycloalkyl)-2-butynyl)acetamides

A series of substituted azacycloalkyl analogues of the muscarinic agonist UH 5 were synthesized and evaluated pharmacologically.

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Bibliographic Details
Published in:Journal of medicinal chemistry 1991-01, Vol.34 (3), p.1073-1079
Main Authors: Bradbury, B J, Baumgold, J, Paek, R, Kammula, U, Zimmet, J, Jacobson, KA
Format: Article
Language:English
Subjects:
acetylcholine
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Description
Summary:A series of substituted azacycloalkyl analogues of the muscarinic agonist UH 5 were synthesized and evaluated pharmacologically.
ISSN:0022-2623