Treatment of acute toxoplasmosis with intravenous clindamycin

The interim results are presented of an ongoing large-scale, prospective, randomized study to determine the potential role of clindamycin in the treatment of toxoplasmic encephalitis. Data was available on 33 patients, 15 of whom received pyrimethamine p.o./clindamycin i.v. and then p.o., and 18 of...

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Published in:European journal of clinical microbiology & infectious diseases 1991-03, Vol.10 (3), p.193-195
Main Authors: DANNEMANN, B. R, MCCUTCHAN, J. A, HESELTINE, P. N. C, LEEDOM, J. M, CLUMECK, N, MORLAT, P, REMINGTON, J. S, ISRAELSKI, D. M, ANTONISKIS, D, LEPORT, C, LUFT, B. J, CHIU, J, VILDE, J. L, NUSSBAUM, J. N, ORELLANA, M
Format: Article
Language:English
Subjects:
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antiparasitic agents
Biological and medical sciences
Medical sciences
Pharmacology. Drug treatments
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Summary:The interim results are presented of an ongoing large-scale, prospective, randomized study to determine the potential role of clindamycin in the treatment of toxoplasmic encephalitis. Data was available on 33 patients, 15 of whom received pyrimethamine p.o./clindamycin i.v. and then p.o., and 18 of whom received pyrimethamine p.o./sulfadiazine p.o. The interim evaluation did not reveal a remarkable difference between the two regimens in the clinical or radiologic response.
ISSN:0934-9723
1435-4373
DOI:10.1007/BF01964461