Strain differentiation of capsule type 23 penicillin‐resistant Streptococcus pneumoniae from nosocomial infections by pyrolysis mass spectrometry

Sixteen isolates of penicillin‐resistant Streptococcus pneumoniae (penicillin‐resistant pneumococci, PRP) serotype 23 with identical antibiograms were examined by pyrolysis mass spectrometry (PYMS) as a possible method of rapid inter‐strain comparison. Some of the isolates were from well‐documented...

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Bibliographic Details
Published in:Letters in applied microbiology 1991-01, Vol.13 (1), p.28-31
Main Authors: Freeman, R., Gould, F.K., Sisson, P.R., Lightfoot, N.F.
Format: Article
Language:English
Subjects:
Bacteriological methods and techniques used in bacteriology
Bacteriology
Biological and medical sciences
Fundamental and applied biological sciences. Psychology
Microbiology
Streptococcus pneumoniae
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Summary:Sixteen isolates of penicillin‐resistant Streptococcus pneumoniae (penicillin‐resistant pneumococci, PRP) serotype 23 with identical antibiograms were examined by pyrolysis mass spectrometry (PYMS) as a possible method of rapid inter‐strain comparison. Some of the isolates were from well‐documented hospital outbreaks of PRP infection whilst others were sporadic isolates. The results were in good agreement with the epidemiological data and showed that PYMS can distinguish strains within a single serotype of Strep. pneumoniae. Pyrolysis mass spectrometry is an attractive technique for the identification and management of nosocomial infections with penicillin‐resistant strains of Strep. pneumoniae.
ISSN:0266-8254
1472-765X
DOI:10.1111/j.1472-765X.1991.tb00561.x