Effects of stimulating the central gray matter on neuronal activity in the activity in the trigeminal nucleus

A comparative study was conducted on the effects of stimulating different central gray matter (CGM) areas on neuronal activity of the trigeminal nucleus during nociceptive stimulation before and after complete section of medial brainstem structures. The possible role of opiate and nonopiate systems...

Full description

Saved in:
Bibliographic Details
Published in:Neurophysiology (New York) 1990-01, Vol.22 (3), p.289-295
Main Authors: Abzianidze, E V, Butkhurzi, S M, Berishvili, V G, Begeladze, LA
Format: Article
Language:English
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A comparative study was conducted on the effects of stimulating different central gray matter (CGM) areas on neuronal activity of the trigeminal nucleus during nociceptive stimulation before and after complete section of medial brainstem structures. The possible role of opiate and nonopiate systems in inhibition of nociceptive afferents is discussed. The CGM was found to be a functionally diverse structure: pain-suppressing and pain-promoting systems exist side by side at this site. The inhibitory influence of the ventromedial CGM is exerted by activation of raphe nucleus neurons; that of the dorsomedial area could well be mediated by involvement of the lateral bulbar area and/or activation of rostral brain structures.
ISSN:0090-2977