Colocalization of GABA sub(A) and NMDA receptors within the dorsal motor nucleus of the vagus nerve (DMV) of the rat

Changes in gastric motor activity are observed in response to glutamate and GABA in the DMV. We investigated the expression of GABAA and NMDA receptors within DMV neurons projecting to the stomach using pseudorabies virus (PRV). PRV immunoreactive (PRV-IR) cells expressing GABAA alpha 1-IR, also exp...

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Bibliographic Details
Published in:Brain research 1997-07, Vol.763 (1), p.123-126
Main Authors: Broussard, D L, Li, Hong, Altschuler, S M
Format: Article
Language:English
Subjects:
pseudorabies virus
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Summary:Changes in gastric motor activity are observed in response to glutamate and GABA in the DMV. We investigated the expression of GABAA and NMDA receptors within DMV neurons projecting to the stomach using pseudorabies virus (PRV). PRV immunoreactive (PRV-IR) cells expressing GABAA alpha 1-IR, also expressed NMDAR1 suggesting that NMDA and GABAA receptors are colocalized. These results provide a neuroanatomical basis for these receptors jointly playing a role in gastric motor functions.
ISSN:0006-8993