Reactivity of monoclonal antibodies to the 41-kilodalton protein of porcine group C rotavirus with homologous and heterologous rotavirus serogroups in immunofluorescence tests

Three monoclonal antibodies (MAbs) to porcine group C rotavirus immunoprecipitated the major inner capsid protein (41 kDa) but failed to precipitate group A rotavirus proteins. In immunofluorescence tests of rotavirus-infected cell cultures or pig intestines, the MAbs recognized porcine and bovine g...

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Bibliographic Details
Published in:Journal of Clinical Microbiology 1991-09, Vol.29 (9), p.2051-2055
Main Authors: Ojeh, C.K. (University of Ibadan, Ibadan, Nigeria), Jiang, B.M, Tsunemitsu, H, Kang, S.Y, Weilnau, P.A, Saif, L.J
Format: Article
Language:English
Subjects:
Animals
Antibodies, Monoclonal
Antibodies, Viral
Antibody Specificity
ANTICORPS MONOCLONAL
ANTICUERPOS MONOCLONALES
ANTIGENE
ANTIGENOS
BOVIN
Capsid - chemistry
Capsid - immunology
CERDO
CULTIVO DE CELULAS
CULTURE DE CELLULE
Female
Fluorescent Antibody Technique
GANADO BOVINO
INTESTIN
INTESTINOS
MEMBRANA MUCOSA
Mice
Molecular Weight
MUQUEUSE
PORCIN
PROTEINAS
PROTEINE
ROTAVIRUS
Rotavirus - classification
Rotavirus - immunology
Rotavirus Infections - immunology
SEROTIPOS
SEROTYPE
Serotyping
Swine
VIRUS
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Description
Summary:Three monoclonal antibodies (MAbs) to porcine group C rotavirus immunoprecipitated the major inner capsid protein (41 kDa) but failed to precipitate group A rotavirus proteins. In immunofluorescence tests of rotavirus-infected cell cultures or pig intestines, the MAbs recognized porcine and bovine group C rotaviruses but not group A or B rotaviruses. These MAbs may recognize the group C rotavirus counterpart to VP6 of group A rotaviruses and may be useful as diagnostic reagents
ISSN:0095-1137
1098-660X
DOI:10.1128/JCM.29.9.2051-2055.1991