Cytomegalovirus Retinitis: Decreased Risk of Bilaterality with Increased Use of Systemic Treatment

Cytomegalovirus (CMV) retinitis may be treated systemically or intravitreally. We reviewed retrospectively patients with CMV retinitis, in order to determine whether systemic treatment was associated with less spread of CMV retinitis from one eye to the other. Of 222 cases, 92 patients had bilateral...

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Bibliographic Details
Published in:Clinical infectious diseases 1997-04, Vol.24 (4), p.620-624
Main Authors: Stalder, Nicole, Sudre, Philippe, Olmari, Maya, Opravil, Milos, Gabriel, Victor, Sansonetti, Alessandra, Overbeck, Jan von, Herbort, Carl P., Hirschel, Bernard
Format: Article
Language:English
Subjects:
AIDS
Biological and medical sciences
Clinical Articles
Cohort studies
Cytomegalovirus
Cytomegalovirus retinitis
Eyes
HIV
Human viral diseases
Infectious diseases
Medical sciences
Ophthalmology
Predisposing factors
Retinitis
University hospitals
Viral diseases
Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye
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Summary:Cytomegalovirus (CMV) retinitis may be treated systemically or intravitreally. We reviewed retrospectively patients with CMV retinitis, in order to determine whether systemic treatment was associated with less spread of CMV retinitis from one eye to the other. Of 222 cases, 92 patients had bilateral disease at onset of CMV retinitis, leaving 130 for analysis. Bilaterality occurred in 10 patients during 12,687 days of systemic treatment and in 34 during 14,791 days without systemic treatment (odds ratio [OR] = 2.92; confidence interval [CI], 1.44-5.90). Patients who had received systemic treatment for
ISSN:1058-4838
1537-6591
DOI:10.1093/clind/24.4.620