Glycine betaine and proline are the principal compatible solutes of Staphylococcus aureus

The foodborne pathogen Staphylococcus aureus is distinguished by its ability to grow within environments of extremely high osmolarity (e.g., foods with low water activity values). In the present study, we examined the accumulation of intracellular organic solutes within S. aureus strain ATCC 12600 w...

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Bibliographic Details
Published in:Current microbiology 1991-09, Vol.23 (3), p.131-137
Main Authors: MILLER, K. J, ZELT, S. C, JI-HYUN BAE
Format: Article
Language:English
Subjects:
Bacteriology
Biological and medical sciences
Fundamental and applied biological sciences. Psychology
Microbiology
Permeability, membrane transport, intracellular transport
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Summary:The foodborne pathogen Staphylococcus aureus is distinguished by its ability to grow within environments of extremely high osmolarity (e.g., foods with low water activity values). In the present study, we examined the accumulation of intracellular organic solutes within S. aureus strain ATCC 12600 when cells were grown in a complex medium containing high concentrations of NaCl. Consistent with previous reports, intracellular proline was found to accumulate to high concentrations. However, NMR spectroscopy of cell extracts revealed glycine betaine to be the predominant intracellular organic solute accumulated within cells grown at high osmolarity.
ISSN:0343-8651
1432-0991
DOI:10.1007/BF02091971