An outbreak of colonisation or infection by Corynebacterium jeikeium reanalysed by pyrolysis-mass spectrometry

A pyrolysis-mass spectrometry (Py-MS) analysis of isolates of Corynebacterium jeikeium broadly confirmed the course of an outbreak previously defined by analysis of plasmid structure. Plasmidless isolates could not be assessed by the initial plasmid profiling and had had to be disregarded. Py-MS ana...

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Bibliographic Details
Published in:Journal of analytical and applied pyrolysis 1997, Vol.40, p.105-110
Main Authors: Sisson, P.R., Freeman, R., Noble, W.C.
Format: Article
Language:English
Subjects:
Corynebacterium jeikeium
Pyrolysis
Pyrolysis-mass spectrometry
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Summary:A pyrolysis-mass spectrometry (Py-MS) analysis of isolates of Corynebacterium jeikeium broadly confirmed the course of an outbreak previously defined by analysis of plasmid structure. Plasmidless isolates could not be assessed by the initial plasmid profiling and had had to be disregarded. Py-MS analysis demonstrated that these were part of the outbreak. The clustering of isolates achieved by Py-MS accorded with the progression of two plasmids through a set of isolates of C. jeikelum which were otherwise closely related to each other. However, the loose structure of the Py-MS clusters may reflect genetic drift in C. jeikeium, which has been proposed in other studies.
ISSN:0165-2370
1873-250X
DOI:10.1016/S0165-2370(97)00012-0