Application of nonsingular transformation to on-line optimal control of poly- β-hydroxybutyrate fermentation

A poly- β-hydroxybutyric acid (PHB) production model has been proposed and is used to calculate the optimal profiles. Feedforward concentration control, off-line optimal control, and on-line optimal control algorithms are applied to enhance the PHB productivity. When an off-line optimal control algo...

Full description

Saved in:
Bibliographic Details
Published in:Journal of biotechnology 1997-07, Vol.55 (3), p.135-150
Main Authors: Lee, Jung Heon, Lim, Henry C., Hong, Juan
Format: Article
Language:English
Subjects:
Bacteriology
Biological and medical sciences
Fundamental and applied biological sciences. Psychology
Growth, nutrition, cell differenciation
Microbiology
Off-line optimal control algorithm
On-line optimal control algorithm
Poly- β-hydroxybutyric acid
Productivity
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A poly- β-hydroxybutyric acid (PHB) production model has been proposed and is used to calculate the optimal profiles. Feedforward concentration control, off-line optimal control, and on-line optimal control algorithms are applied to enhance the PHB productivity. When an off-line optimal control algorithm was applied, the resulting profiles of glucose and ammonium chloride concentration were different from those calculated from the model. Therefore, an on-line control algorithm was necessary to compensate for the errors between the model prediction and actual measurements. By applying the on-line optimal control algorithm, the final PHB concentration was increased to 17.1 g/l which compares favorably with 13.9 g/l obtained with the off-line optimal control.
ISSN:0168-1656
1873-4863
DOI:10.1016/S0168-1656(97)00064-3