Crystalline cellulose degradation: new insight into the function of cellobiohydrolases

Cellulose is an important industrial raw material and a source of renewable energy. The crystalline structure of cellulose is biodegradable by the combined activities of many different enzymes. Cellobiohydrolases, the key cellulases, have extended tunnel-shaped active sites. Owing to the design of t...

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Bibliographic Details
Published in:Trends in biotechnology (Regular ed.) 1997-05, Vol.15 (5), p.160-167
Main Author: Teeri, Tuula T.
Format: Article
Language:English
Subjects:
Biological and medical sciences
Biotechnology
cellulases
Fundamental and applied biological sciences. Psychology
Methods. Procedures. Technologies
Others
Various methods and equipments
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Summary:Cellulose is an important industrial raw material and a source of renewable energy. The crystalline structure of cellulose is biodegradable by the combined activities of many different enzymes. Cellobiohydrolases, the key cellulases, have extended tunnel-shaped active sites. Owing to the design of their active-site tunnels, they do not make cuts within cellulose chains but release cellobiose from the chain ends. Cellobiohydrolases may therefore prove to be useful for achieving subtle modifications of fiber properties in paper or textiles without the loss of fiber strength commonly observed with other cellulases.
ISSN:0167-7799
1879-3096
DOI:10.1016/S0167-7799(97)01032-9