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Effects of BDE-209 and its mixtures with BDE-47 and BDE-99 on multiple biomarkers in Carassius auratus

Highlights • Biomarkers including AChE, EROD, GST, SOD and CAT were used. • The toxicity order of PBDEs was proposed via the integrated biomarker response. • The mixtures showed more negative biological effects than BDE-209 alone.

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Published in:	Environmental toxicology and pharmacology 2014-09, Vol.38 (2), p.554-561
Main Authors:	Xie, Zhengxin, Lu, Guanghua, Qi, Pengde
Format:	Article
Language:	English
Subjects:	Acetylcholinesterase - metabolism Animals BDE-209 Biomarker Biomarkers - metabolism Brain - drug effects Brain - enzymology Carassius auratus Catalase - metabolism Cytochrome P-450 CYP1A1 - metabolism Dose-Response Relationship, Drug Emergency Fish Proteins - metabolism Gene Expression Regulation, Enzymologic - drug effects Goldfish - metabolism Halogenated Diphenyl Ethers - toxicity IBR Liver - drug effects Liver - enzymology Superoxide Dismutase - metabolism Water Pollutants, Chemical - toxicity
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container_title	Environmental toxicology and pharmacology
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description	Highlights • Biomarkers including AChE, EROD, GST, SOD and CAT were used. • The toxicity order of PBDEs was proposed via the integrated biomarker response. • The mixtures showed more negative biological effects than BDE-209 alone.
doi_str_mv	10.1016/j.etap.2014.08.008
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source	ScienceDirect Freedom Collection 2022-2024
subjects	Acetylcholinesterase - metabolism Animals BDE-209 Biomarker Biomarkers - metabolism Brain - drug effects Brain - enzymology Carassius auratus Catalase - metabolism Cytochrome P-450 CYP1A1 - metabolism Dose-Response Relationship, Drug Emergency Fish Proteins - metabolism Gene Expression Regulation, Enzymologic - drug effects Goldfish - metabolism Halogenated Diphenyl Ethers - toxicity IBR Liver - drug effects Liver - enzymology Superoxide Dismutase - metabolism Water Pollutants, Chemical - toxicity
title	Effects of BDE-209 and its mixtures with BDE-47 and BDE-99 on multiple biomarkers in Carassius auratus
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