Hypopharyngeal cancer incidence, treatment, and survival: Temporal trends in the United States

Objectives/Hypothesis The objective was to characterize incidence, treatment, and survival for hypopharyngeal cancer in the United States between 1988 and 2010, and to analyze associations between changes in treatment modality and survival. Study Design Retrospective cohort study. Methods A total of...

Full description

Saved in:
Bibliographic Details
Published in:The Laryngoscope 2014-09, Vol.124 (9), p.2064-2069
Main Authors: Kuo, Phoebe, Chen, Michelle M., Decker, Roy H., Yarbrough, Wendell G., Judson, Benjamin L.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Aged, 80 and over
Cancer
Cohort Studies
Female
head and neck cancer
Humans
hypopharyngeal cancer
Hypopharyngeal Neoplasms - epidemiology
Hypopharyngeal Neoplasms - therapy
Hypopharynx
Incidence
Laryngectomy
Male
Middle Aged
Multivariate analysis
Pharyngectomy
Radiation therapy
Retrospective Studies
Surgery
survival
Survival Rate
Time Factors
Trends
United States - epidemiology
Young Adult
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objectives/Hypothesis The objective was to characterize incidence, treatment, and survival for hypopharyngeal cancer in the United States between 1988 and 2010, and to analyze associations between changes in treatment modality and survival. Study Design Retrospective cohort study. Methods A total of 3,958 adult patients with hypopharyngeal cancer were identified in the Surveillance, Epidemiology, and End Results database. Incidence, treatment, and survival, controlling for patient demographics and disease severity, were analyzed using two‐tailed t tests, Kaplan‐Meier analysis, and univariate and multivariate Cox regression. Results The incidence of hypopharyngeal cancer decreased from 1973 to 2010 with an average annual percent change (APC) of −2.0% every year (P 
ISSN:0023-852X
1531-4995
DOI:10.1002/lary.24651