Microviscosity of mouse splenocyte cytoplasmic membrane modified by some antibiotics

This study has assessed the changes in the polarization fluorescence of 1,6-diphenyl-1,3,5-hexatriene in the splenic membrane of mice treated with clindamycin, penicillin, cefoxitin, cefamandole, cephaloridine, tetracycline, and erythromycin. The data show that most of the antibiotics tested modifie...

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Bibliographic Details
Published in:Current microbiology 1991-03, Vol.22 (3), p.195-197
Main Authors: GALDIERO, F, ROMANO CARRATELLI, C, BENTIVOGLIO, C, NUZZO, I, GALDIERO, M
Format: Article
Language:English
Subjects:
Antibacterial agents
Antibiotics. Antiinfectious agents. Antiparasitic agents
Biological and medical sciences
cefoxitin
cell membranes
Medical sciences
penicillin
Pharmacology. Drug treatments
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Summary:This study has assessed the changes in the polarization fluorescence of 1,6-diphenyl-1,3,5-hexatriene in the splenic membrane of mice treated with clindamycin, penicillin, cefoxitin, cefamandole, cephaloridine, tetracycline, and erythromycin. The data show that most of the antibiotics tested modified membrane activity, as was shown by the changes in membrane microviscosity parameters.
ISSN:0343-8651
1432-0991
DOI:10.1007/BF02092134