Pre-flight assessment in patients with obesity hypoventilation syndrome

Background and objective Reduced atmospheric pressure during air travel can cause significant hypoxaemia in some patients with respiratory disease. Our aims were to investigate the degree of hypoxaemia in patients with obesity hypoventilation syndrome (OHS) during hypoxic challenge test (HCT), and t...

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Bibliographic Details
Published in:Respirology (Carlton, Vic.) Vic.), 2014-11, Vol.19 (8), p.1229-1232
Main Authors: Ali, Masood, Smith, Ian E., Gulati, Atul, Shneerson, John M.
Format: Article
Language:English
Subjects:
Aged
Air Travel
Blood Gas Analysis
Body Mass Index
Breath Tests - methods
Female
Humans
Hypoxia - etiology
Hypoxia - prevention & control
hypoxic challenge test
Male
Middle Aged
Noninvasive Ventilation - methods
obesity
obesity hypoventilation syndrome
Obesity Hypoventilation Syndrome - blood
Obesity Hypoventilation Syndrome - complications
Obesity Hypoventilation Syndrome - diagnosis
Obesity Hypoventilation Syndrome - physiopathology
obstructive sleep apnoea
Oxygen Inhalation Therapy - methods
Respiration
Respiratory Insufficiency - etiology
Respiratory Insufficiency - prevention & control
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Summary:Background and objective Reduced atmospheric pressure during air travel can cause significant hypoxaemia in some patients with respiratory disease. Our aims were to investigate the degree of hypoxaemia in patients with obesity hypoventilation syndrome (OHS) during hypoxic challenge test (HCT), and to identify any predictors of a positive HCT. Methods Thirteen patients underwent assessment, including HCT, lung function and incremental shuttle walk test. All had OHS well controlled with long‐term nocturnal non‐invasive ventilation (NIV). Patients with chronic obstructive pulmonary disease were excluded. A positive HCT was defined according to the British Thoracic Society (BTS) recommendation as arterial oxygen tension (PaO2) 
ISSN:1323-7799
1440-1843
DOI:10.1111/resp.12353