Validity of a clinical decision rule-based alert system for drug dose adjustment in patients with renal failure intended to improve pharmacists’ analysis of medication orders in hospitals

Highlights • We compared the diagnostic performances of an alerts system with pharmacists. • The alert system and the pharmacists showed a relatively poor inter-rater agreement. • The alert system fired more appropriate alerts and made fewer errors. • Non-interruptive mode for some alerts can enhanc...

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Bibliographic Details
Published in:International journal of medical informatics (Shannon, Ireland) Ireland), 2013-10, Vol.82 (10), p.964-972
Main Authors: Boussadi, A, Caruba, T, Karras, A, Berdot, S, Degoulet, P, Durieux, P, Sabatier, B
Format: Article
Language:English
Subjects:
Adverse Drug Reaction Reporting Systems - statistics & numerical data
Clinical Pharmacy Information Systems - statistics & numerical data
Computer-assisted
Decision Support Systems, Clinical
Decision support techniques
Drug dosage calculations
Drug prescriptions
Drug Therapy, Computer-Assisted - methods
Drug Therapy, Computer-Assisted - statistics & numerical data
Electronic Prescribing - statistics & numerical data
France
Humans
Internal Medicine
Medical Order Entry Systems - statistics & numerical data
Medication Errors - prevention & control
Medication Errors - statistics & numerical data
Medication Systems, Hospital - statistics & numerical data
Other
Pharmaceutical preparations/administration & dosage
Pharmacists - statistics & numerical data
Renal Insufficiency - diagnosis
Renal Insufficiency - drug therapy
Software validation
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Summary:Highlights • We compared the diagnostic performances of an alerts system with pharmacists. • The alert system and the pharmacists showed a relatively poor inter-rater agreement. • The alert system fired more appropriate alerts and made fewer errors. • Non-interruptive mode for some alerts can enhance the safety of drug prescriptions.
ISSN:1386-5056
1872-8243
DOI:10.1016/j.ijmedinf.2013.06.006