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Mutation analysis of the IL36RN gene in Chinese patients with generalized pustular psoriasis with/without psoriasis vulgaris
Highlights • Six IL36RN variants were found in 29 GPP patients, 12 PV cases and 6 controls. • The variants’ frequencies were different between GPP and PV groups. • There were also significant differences between GPP alone and GPP with PV groups. • Demonstrated that GPP and PV are distinct subtypes o...
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| Published in: | Journal of dermatological science 2014-11, Vol.76 (2), p.132-138 |
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| Main Authors: | , , , , , , , , , , , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c447t-9032c43371417cfc6aeb7f6979764d79d1fbdaa62598ae87279a0a1a1a7a8d423 |
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| cites | cdi_FETCH-LOGICAL-c447t-9032c43371417cfc6aeb7f6979764d79d1fbdaa62598ae87279a0a1a1a7a8d423 |
| container_end_page | 138 |
| container_issue | 2 |
| container_start_page | 132 |
| container_title | Journal of dermatological science |
| container_volume | 76 |
| creator | Li, Xiuyan Chen, Mingfei Fu, Xi’an Zhang, Qilin Wang, Zhenzhen Yu, Gongqi Yu, Yongxiang Qin, Peipei Wu, Weizhi Pan, Futang Liu, Hong Zhang, Furen |
| description | Highlights • Six IL36RN variants were found in 29 GPP patients, 12 PV cases and 6 controls. • The variants’ frequencies were different between GPP and PV groups. • There were also significant differences between GPP alone and GPP with PV groups. • Demonstrated that GPP and PV are distinct subtypes of psoriasis on the etiology. • GPP alone may be regarded as an especial entities of GPP different from GPP with PV. |
| doi_str_mv | 10.1016/j.jdermsci.2014.08.007 |
| format | article |
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Published by Elsevier Ireland Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c447t-9032c43371417cfc6aeb7f6979764d79d1fbdaa62598ae87279a0a1a1a7a8d423</citedby><cites>FETCH-LOGICAL-c447t-9032c43371417cfc6aeb7f6979764d79d1fbdaa62598ae87279a0a1a1a7a8d423</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25212972$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Li, Xiuyan</creatorcontrib><creatorcontrib>Chen, Mingfei</creatorcontrib><creatorcontrib>Fu, Xi’an</creatorcontrib><creatorcontrib>Zhang, Qilin</creatorcontrib><creatorcontrib>Wang, Zhenzhen</creatorcontrib><creatorcontrib>Yu, Gongqi</creatorcontrib><creatorcontrib>Yu, Yongxiang</creatorcontrib><creatorcontrib>Qin, Peipei</creatorcontrib><creatorcontrib>Wu, Weizhi</creatorcontrib><creatorcontrib>Pan, Futang</creatorcontrib><creatorcontrib>Liu, Hong</creatorcontrib><creatorcontrib>Zhang, Furen</creatorcontrib><title>Mutation analysis of the IL36RN gene in Chinese patients with generalized pustular psoriasis with/without psoriasis vulgaris</title><title>Journal of dermatological science</title><addtitle>J Dermatol Sci</addtitle><description>Highlights • Six IL36RN variants were found in 29 GPP patients, 12 PV cases and 6 controls. • The variants’ frequencies were different between GPP and PV groups. • There were also significant differences between GPP alone and GPP with PV groups. • Demonstrated that GPP and PV are distinct subtypes of psoriasis on the etiology. • GPP alone may be regarded as an especial entities of GPP different from GPP with PV.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Animals</subject><subject>Asians - genetics</subject><subject>Cats</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Dermatology</subject><subject>DNA Mutational Analysis</subject><subject>Female</subject><subject>Generalized pustular psoriasis (GPP)</subject><subject>GPP with preceding, later or accompanied by PV (GPP with PV)</subject><subject>GPP without psoriasis PV (GPP alone)</subject><subject>Humans</subject><subject>Interleukin 36 receptor antagonist (IL36RN)</subject><subject>Interleukins - genetics</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Mutation</subject><subject>Mutation analysis</subject><subject>Psoriasis - genetics</subject><subject>Psoriasis vulgaris (PV)</subject><issn>0923-1811</issn><issn>1873-569X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><recordid>eNqFkV2L1DAUhoMo7rj6F5ZcetPuSdJJmhtRBj8WRgU_wLuQSU93UjttTdKVEX-8qbMr4o0EkpA85z2c9yXkgkHJgMnLruwaDIfofMmBVSXUJYC6R1asVqJYS_3lPlmB5qJgNWNn5FGMHQCseaUfkjO-5oxrxVfk59s52eTHgdrB9sfoIx1bmvZIr7ZCfnhHr3FA6ge62fsBI9Ip0zikSL_7tP_9G2zvf2BDpzmmubeBTnEM3i5SC3O5bOOc_nq-mftrG3x8TB60to_45PY8J59fvfy0eVNs37--2rzYFq6qVCo0CO4qIRSrmHKtkxZ3qpVaaSWrRumGtbvGWsnXurZYK660BcvyUrZuKi7OydOT7hTGbzPGZA4-Oux7O-A4R8Mk41yDBJFReUJdGGMM2Jop-IMNR8PALM6bztw5bxbnDdQmO58LL257zLsDNn_K7qzOwPMTgHnSG4_BZAkcHDY-oEumGf3_ezz7R8L1fvDO9l_xiLEb55BDzPOYyA2Yj0v-S_ysAmD5Ln4BqRCvUQ</recordid><startdate>20141101</startdate><enddate>20141101</enddate><creator>Li, Xiuyan</creator><creator>Chen, Mingfei</creator><creator>Fu, Xi’an</creator><creator>Zhang, Qilin</creator><creator>Wang, Zhenzhen</creator><creator>Yu, Gongqi</creator><creator>Yu, Yongxiang</creator><creator>Qin, Peipei</creator><creator>Wu, Weizhi</creator><creator>Pan, Futang</creator><creator>Liu, Hong</creator><creator>Zhang, Furen</creator><general>Elsevier Ireland Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20141101</creationdate><title>Mutation analysis of the IL36RN gene in Chinese patients with generalized pustular psoriasis with/without psoriasis vulgaris</title><author>Li, Xiuyan ; Chen, Mingfei ; Fu, Xi’an ; Zhang, Qilin ; Wang, Zhenzhen ; Yu, Gongqi ; Yu, Yongxiang ; Qin, Peipei ; Wu, Weizhi ; Pan, Futang ; Liu, Hong ; Zhang, Furen</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c447t-9032c43371417cfc6aeb7f6979764d79d1fbdaa62598ae87279a0a1a1a7a8d423</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Animals</topic><topic>Asians - genetics</topic><topic>Cats</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Dermatology</topic><topic>DNA Mutational Analysis</topic><topic>Female</topic><topic>Generalized pustular psoriasis (GPP)</topic><topic>GPP with preceding, later or accompanied by PV (GPP with PV)</topic><topic>GPP without psoriasis PV (GPP alone)</topic><topic>Humans</topic><topic>Interleukin 36 receptor antagonist (IL36RN)</topic><topic>Interleukins - genetics</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Mutation</topic><topic>Mutation analysis</topic><topic>Psoriasis - genetics</topic><topic>Psoriasis vulgaris (PV)</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Li, Xiuyan</creatorcontrib><creatorcontrib>Chen, Mingfei</creatorcontrib><creatorcontrib>Fu, Xi’an</creatorcontrib><creatorcontrib>Zhang, Qilin</creatorcontrib><creatorcontrib>Wang, Zhenzhen</creatorcontrib><creatorcontrib>Yu, Gongqi</creatorcontrib><creatorcontrib>Yu, Yongxiang</creatorcontrib><creatorcontrib>Qin, Peipei</creatorcontrib><creatorcontrib>Wu, Weizhi</creatorcontrib><creatorcontrib>Pan, Futang</creatorcontrib><creatorcontrib>Liu, Hong</creatorcontrib><creatorcontrib>Zhang, Furen</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of dermatological science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Li, Xiuyan</au><au>Chen, Mingfei</au><au>Fu, Xi’an</au><au>Zhang, Qilin</au><au>Wang, Zhenzhen</au><au>Yu, Gongqi</au><au>Yu, Yongxiang</au><au>Qin, Peipei</au><au>Wu, Weizhi</au><au>Pan, Futang</au><au>Liu, Hong</au><au>Zhang, Furen</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Mutation analysis of the IL36RN gene in Chinese patients with generalized pustular psoriasis with/without psoriasis vulgaris</atitle><jtitle>Journal of dermatological science</jtitle><addtitle>J Dermatol Sci</addtitle><date>2014-11-01</date><risdate>2014</risdate><volume>76</volume><issue>2</issue><spage>132</spage><epage>138</epage><pages>132-138</pages><issn>0923-1811</issn><eissn>1873-569X</eissn><abstract>Highlights • Six IL36RN variants were found in 29 GPP patients, 12 PV cases and 6 controls. • The variants’ frequencies were different between GPP and PV groups. • There were also significant differences between GPP alone and GPP with PV groups. • Demonstrated that GPP and PV are distinct subtypes of psoriasis on the etiology. • GPP alone may be regarded as an especial entities of GPP different from GPP with PV.</abstract><cop>Netherlands</cop><pub>Elsevier Ireland Ltd</pub><pmid>25212972</pmid><doi>10.1016/j.jdermsci.2014.08.007</doi><tpages>7</tpages></addata></record> |
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| ispartof | Journal of dermatological science, 2014-11, Vol.76 (2), p.132-138 |
| issn | 0923-1811 1873-569X |
| language | eng |
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| source | ScienceDirect Journals |
| subjects | Adolescent Adult Animals Asians - genetics Cats Child Child, Preschool Dermatology DNA Mutational Analysis Female Generalized pustular psoriasis (GPP) GPP with preceding, later or accompanied by PV (GPP with PV) GPP without psoriasis PV (GPP alone) Humans Interleukin 36 receptor antagonist (IL36RN) Interleukins - genetics Male Middle Aged Mutation Mutation analysis Psoriasis - genetics Psoriasis vulgaris (PV) |
| title | Mutation analysis of the IL36RN gene in Chinese patients with generalized pustular psoriasis with/without psoriasis vulgaris |
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