Equivalence of outcomes for rural and metropolitan patients with metastatic colorectal cancer in South Australia

Objective: To compare the management and outcome of rural and metropolitan patients with metastatic colorectal cancer (mCRC) in South Australia. Design, setting and patients: Retrospective cohort study of patients with mCRC submitted to the South Australian mCRC registry between 2 February 2006 and...

Full description

Saved in:
Bibliographic Details
Published in:Medical journal of Australia 2014-10, Vol.201 (8), p.462-466
Main Authors: Hocking, Christopher, Broadbridge, Vy Tuong, Karapetis, Christos, Beeke, Carol, Padbury, Robert, Maddern, Guy J, Roder, David M, Price, Timothy J
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Colonoscopy - methods
Colorectal Neoplasms - epidemiology
Colorectal Neoplasms - secondary
Colorectal Neoplasms - therapy
Combined Modality Therapy
Computer Simulation
Female
Follow-Up Studies
Humans
Male
Mass Screening - methods
Middle Aged
Morbidity - trends
Neoplasm Metastasis
Neoplasms
Prognosis
Retrospective Studies
ROC Curve
Rural Population
South Australia - epidemiology
Survival Rate - trends
Time Factors
Young Adult
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objective: To compare the management and outcome of rural and metropolitan patients with metastatic colorectal cancer (mCRC) in South Australia. Design, setting and patients: Retrospective cohort study of patients with mCRC submitted to the South Australian mCRC registry between 2 February 2006 and a cut‐off date of 28 May 2012. Main outcome measures: Differences in oncological and surgical management and overall survival (calculated using the Kaplan–Meier method) between city and rural patients. Results: Of 2289 patients, 624 (27.3%) were rural. There was a higher proportion of male patients in the rural cohort, but other patient characteristics did not significantly differ between the cohorts. Equivalent rates of chemotherapy administration between city and rural patients were observed across each line of treatment (first line: 56.0% v 58.3%, P = 0.32; second line: 23.3% v 22.5%, P = 0.78; and third line: 10.1% v 9.3%, P = 0.69). A higher proportion of city patients received combination chemotherapy in the first‐line setting (67.4% v 59.9%; P = 0.01). When an oxaliplatin combination was prescribed, oral capecitabine was used more frequently in rural patients (22.9% v 8.4%; P 
ISSN:0025-729X
1326-5377
DOI:10.5694/mja14.00046