Optimization of fumaric acid production from potato flour by Rhizopus arrhizus

Fumaric acid production by Rhizopus arrhizus from potato flour was studied at different initial substrate concentrations (S), C/N ratios and fermentation times (tF) in a composite design experiment. By using response surface methodology and canonical analysis, the experimental values of fumaric acid...

Full description

Saved in:
Bibliographic Details
Published in:Applied microbiology and biotechnology 1991-10, Vol.36 (1), p.35-39
Main Authors: Moresi, M, Parente, E, Petruccioli, M, Federici, F
Format: Article
Language:English
Subjects:
acid production
Biological and medical sciences
biosynthesis
Biotechnology
carbohydrate metabolism
culture media
fermentation
flour
fumaric acid
Fundamental and applied biological sciences. Psychology
Methods. Procedures. Technologies
Microbial engineering. Fermentation and microbial culture technology
potato flour
Rhizopus arrhizus
Solanum tuberosum
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Fumaric acid production by Rhizopus arrhizus from potato flour was studied at different initial substrate concentrations (S), C/N ratios and fermentation times (tF) in a composite design experiment. By using response surface methodology and canonical analysis, the experimental values of fumaric acid and mycelial biomass yields and productivity were fitted to the only statistically significant factors with mean percentage errors of 11, 26 and 13%, respectively. Owing to the limited statistical significance of the C/N ratio, it was possible to determine the values of S (25-50 g/l of glucose equivalent) and tF (44-100 h) associated with fumaric acid yields ranging from 60 to 75% and productivities varying from 6 to 8.4 g/l per day. Since such results were in quite good agreement with previous experiments carried out on other starchy materials, the above operating conditions might be used to minimise fumaric acid production costs as a function of the feedstock used.
ISSN:0175-7598
1432-0614
DOI:10.1007/BF00164695