Echocardiographic screening for pulmonary arterial hypertension in HIV-positive patients

Human immunodeficiency virus (HIV) infection is associated with an increased risk for pulmonary arterial hypertension (PAH). Upon the screening of 220 asymptomatic HIV-positive individuals by echocardiography, we detected and confirmed HIV-associated PAH in 0.45 % of cases. Mild elevations of systol...

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Bibliographic Details
Published in:Infection 2014-08, Vol.42 (4), p.737-741
Main Authors: ten Freyhaus, H., Vogel, D., Lehmann, C., Kümmerle, T., Wyen, C., Fätkenheuer, G., Rosenkranz, S.
Format: Article
Language:English
Subjects:
Adult
Aged
Brief Report
Cohort Studies
Echocardiography
Family Medicine
Female
General Practice
HIV Infections - complications
Human immunodeficiency virus
Humans
Hypertension
Hypertension, Pulmonary - diagnosis
Hypertension, Pulmonary - epidemiology
Infectious Diseases
Internal Medicine
Male
Mass Screening - methods
Medicine
Medicine & Public Health
Middle Aged
Prospective Studies
Young Adult
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Summary:Human immunodeficiency virus (HIV) infection is associated with an increased risk for pulmonary arterial hypertension (PAH). Upon the screening of 220 asymptomatic HIV-positive individuals by echocardiography, we detected and confirmed HIV-associated PAH in 0.45 % of cases. Mild elevations of systolic pulmonary arterial pressure most probably owing to left ventricular diastolic dysfunction were found in 7.7 % of cases, without progress after 2 years. We suggest that the screening of asymptomatic HIV-positive patients for PAH should not be performed.
ISSN:0300-8126
1439-0973
DOI:10.1007/s15010-014-0610-8