Effect of sustained use of platelet aggregation inhibitors on post-endoscopic sphincterotomy bleeding

Background and Aim The effect of platelet aggregation inhibitors (PAI) on post‐endoscopic sphincterotomy (ES) bleeding in patients who cannot discontinue PAI for sufficient time in urgent conditions has not been identified. The present study analyzed the effect of sustained use of PAI on post‐proced...

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Bibliographic Details
Published in:Digestive endoscopy 2014-11, Vol.26 (6), p.737-744
Main Authors: Lee, Min Geun, Kim, Jaihwan, Lee, Sang Hyub, Lee, Ban Seok, Lee, Seung June, Lee, Yoon Suk, Cha, Byung Hyo, Hwang, Jin-Hyeok, Ryu, Ji Kon, Kim, Yong-Tae
Format: Article
Language:English
Subjects:
acetylsalicylic acid
Aged
endoscopic retrograde cholangiopancreatography (ERCP)
endoscopic sphincterotomy (ES)
Female
gastrointestinal hemorrhage
Humans
Male
Middle Aged
platelet aggregation inhibitor
Platelet Aggregation Inhibitors - therapeutic use
Postoperative Hemorrhage - drug therapy
Postoperative Hemorrhage - etiology
Republic of Korea
Retrospective Studies
Sphincterotomy, Endoscopic - adverse effects
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Summary:Background and Aim The effect of platelet aggregation inhibitors (PAI) on post‐endoscopic sphincterotomy (ES) bleeding in patients who cannot discontinue PAI for sufficient time in urgent conditions has not been identified. The present study analyzed the effect of sustained use of PAI on post‐procedural bleeding in patients undergoing ES. Methods A total of 762 patients were grouped into one of the following groups: no‐PAI group (n = 601), continuation group (n = 132), and withdrawal group (n = 29). The continuation group included sustained PAI therapy (sustained user, n = 49) or those in whom therapy was interrupted
ISSN:0915-5635
1443-1661
DOI:10.1111/den.12271