A family of plant-specific polyketide synthases: facts and predictions

The enzymes involved in the synthesis of chalcones, stilbenes and acridones are closely related plant-specific polyketide synthases. Evidence suggests that they belong to a family of condensing enzymes that catalyse the initial key reactions in the biosynthesis of a group of biologically and pharmac...

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Bibliographic Details
Published in:Trends in plant science 1997-10, Vol.2 (10), p.373-378
Main Author: Schroeder, J
Format: Article
Language:English
Subjects:
Biological and medical sciences
Enzymes
Fundamental and applied biological sciences. Psychology
Metabolism
Plant physiology and development
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Summary:The enzymes involved in the synthesis of chalcones, stilbenes and acridones are closely related plant-specific polyketide synthases. Evidence suggests that they belong to a family of condensing enzymes that catalyse the initial key reactions in the biosynthesis of a group of biologically and pharmaceutically interesting substances. Recent analysis has revealed that related sequences occur in bacteria, suggesting that the protein family is much older than previously assumed.
ISSN:1360-1385
1878-4372
DOI:10.1016/S1360-1385(97)87121-X