The contribution of muscle hypertrophy to strength changes following resistance training

• Published in: European journal of applied physiology 2014-06, Vol.114 (6), p.1239-1249
• Main Authors: Erskine, Robert M., Fletcher, Gareth, Folland, Jonathan P.
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Biomedical and Life Sciences; Biomedicine; Exercise; Human Physiology; Humans; Male; Morphology; Muscle Strength; Muscle, Skeletal - anatomy & histology; Muscle, Skeletal - innervation; Muscle, Skeletal - physiology; Occupational Medicine/Industrial Medicine; Organ Size; Original Article; Physical fitness; Resistance Training; Sports Medicine; Strength training
• ISSN: 1439-6319; 1439-6327
• DOI: 10.1007/s00421-014-2855-4

Purpose Whilst skeletal muscle hypertrophy is considered an important adaptation to resistance training (RT), it has not previously been found to explain the inter-individual changes in strength after RT. This study investigated the contribution of hypertrophy to individual gains in isometric, isoinertial and explosive strength after 12 weeks of elbow flexor RT. Methods Thirty-three previously untrained, healthy men (18–30 years) completed an initial 3-week period of elbow flexor RT (to facilitate neurological responses) followed by 6-week no training, and then 12-week elbow flexor RT. Unilateral elbow flexor muscle strength [isometric maximum voluntary force (iMVF), single repetition maximum (1-RM) and explosive force], muscle volume ( V m ), muscle fascicle pennation angle ( θ p ) and normalized agonist, antagonist and stabilizer sEMG were assessed pre and post 12-week RT. Results Percentage gains in V m correlated with percentage changes in iMVF ( r  = 0.527; P  = 0.002) and 1-RM ( r  = 0.482; P  = 0.005) but not in explosive force ( r  ≤ 0.243; P  ≥ 0.175). Percentage changes in iMVF, 1-RM, and explosive force did not correlate with percentage changes in agonist, antagonist or stabilizer sEMG (all P  > 0.05). Percentage gains in θ p inversely correlated with percentage changes in normalized explosive force at 150 ms after force onset ( r  = 0.362; P  = 0.038). Conclusions We have shown for the first time that muscle hypertrophy explains a significant proportion of the inter-individual variability in isometric and isoinertial strength gains following 12-week elbow flexor RT in healthy young men.