Field effectiveness of hepatitis A vaccine and uptake of post exposure prophylaxis following a change to the Australian guidelines

Highlights • 318 susceptible contacts included in a retrospective cohort. • Compliance with PEP increased from 76% with NHIG to 89% with hepatitis A vaccine. • Vaccine effectiveness in post exposure context estimated at 95.6%. • All 10 contacts subsequently reported with hepatitis A were

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Bibliographic Details
Published in:Vaccine 2014-09, Vol.32 (42), p.5509-5513
Main Authors: Freeman, Evan, Lawrence, Glenda, McAnulty, Jeremy, Tobin, Sean, MacIntyre, C. Raina, Torvaldsen, Siranda
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age
Allergy and Immunology
Applied microbiology
Biological and medical sciences
Child
Child, Preschool
Cohort
Contacts
Disease
Epidemiology
Female
Fundamental and applied biological sciences. Psychology
Hepatitis
Hepatitis A
Hepatitis A - prevention & control
Hepatitis A Vaccines - therapeutic use
Hepatitis A virus
Human viral diseases
Humans
Infant
Infant, Newborn
Infections
Infectious diseases
Information management
Laboratories
Male
Medical sciences
Microbiology
New South Wales
Population
Post-exposure prophylaxis
Post-Exposure Prophylaxis - statistics & numerical data
Practice Guidelines as Topic
Prophylaxis
Public health
Reporting requirements
Retrospective Studies
Vaccine
Vaccines
Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)
Viral diseases
Viral hepatitis
Young Adult
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Description
Summary:Highlights • 318 susceptible contacts included in a retrospective cohort. • Compliance with PEP increased from 76% with NHIG to 89% with hepatitis A vaccine. • Vaccine effectiveness in post exposure context estimated at 95.6%. • All 10 contacts subsequently reported with hepatitis A were
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2014.07.048