Preferential deposition of visceral adipose tissue occurs due to physical inactivity

We hypothesised that strict inactivity (bed rest) would lead to regional differences in fat deposition. Twenty-four male subjects underwent 60d bed rest and remained inactive ( n =9), performed resistance exercise plus whole-body vibration (RVE; n =7) or resistance exercise only (RE; n =8). Fat mass...

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Bibliographic Details
Published in:International Journal of Obesity 2014-11, Vol.38 (11), p.1478-1480
Main Authors: Belavý, D L, Möhlig, M, Pfeiffer, A F H, Felsenberg, D, Armbrecht, G
Format: Article
Language:English
Subjects:
692/420
692/699/317
Absorptiometry
Absorptiometry, Photon
Adipose tissue
Adipose Tissue - metabolism
Adipose tissues
Adult
Bed rest
Bed Rest - adverse effects
Biological and medical sciences
Body composition
Body fat
Bones
Deposition
Dual energy X-ray absorptiometry
Epidemiology
Exercise
Head-Down Tilt - adverse effects
Health Promotion and Disease Prevention
Humans
Iliac crest
Immobilization
Insulin
Internal Medicine
Legs
Lipid metabolism
Male
Medical sciences
Medicine
Medicine & Public Health
Metabolic Diseases
Muscular Atrophy - pathology
Muscular Atrophy - prevention & control
Nutrition
Obesity
Physical fitness
Physiological aspects
Properties
Public Health
Regions
Resistance Training - methods
Sedentary behavior
short-communication
Space Flight
Time Factors
Vibration
Weightlessness Simulation
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Summary:We hypothesised that strict inactivity (bed rest) would lead to regional differences in fat deposition. Twenty-four male subjects underwent 60d bed rest and remained inactive ( n =9), performed resistance exercise plus whole-body vibration (RVE; n =7) or resistance exercise only (RE; n =8). Fat mass was assessed via dual X-ray absorptiometry. In the inactive subjects, fat deposition differed between body regions ( P =0.0005) with android region visceral adipose tissue increasing the most (+29% at the end of bed rest), followed by remainder of the trunk (from chin to the iliac crest; +10%) and the arms and legs (both +7%). Insulin sensitivity reduced in the inactive subjects at the end of bed rest ( P =0.036). RE did not have a significant impact on regional fat mass changes ( P ⩾0.055). In RVE, increases in visceral adipose tissue (−14%; P =0.028 vs inactive subjects) and in the arms (arms −8%, P =0.011 vs inactive) were not seen. We conclude that inactivity leads to a preferential increase in visceral adipose tissue.
ISSN:0307-0565
1476-5497
DOI:10.1038/ijo.2014.26