Distribution of the alpha 7 nicotinic acetylcholine receptor subunit in the developing chick cerebellum

Previous studies of the nicotinic acetylcholine receptor (nAChR) subunits in adult mammalian and avian brains have demonstrated a spatially restricted distribution of these subunits; little, however, is known about the nAChR subunit developmental distribution. The present study demonstrated a transi...

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Bibliographic Details
Published in:Brain research. Developmental brain research 1998-01, Vol.105 (1), p.141-145
Main Authors: Kaneko, WM, Britto, LRG, Lindstrom, J M, Karten, HJ
Format: Article
Language:English
Online Access:Get full text
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Summary:Previous studies of the nicotinic acetylcholine receptor (nAChR) subunits in adult mammalian and avian brains have demonstrated a spatially restricted distribution of these subunits; little, however, is known about the nAChR subunit developmental distribution. The present study demonstrated a transient pattern of distribution of the neuronal nAChR subunit, alpha 7, in the developing chick cerebellum by using immunohistochemical techniques. This transient distribution may suggest a critical period for the development of the cholinergic system in the cerebellum.
ISSN:0165-3806
DOI:10.1016/S0165-3806(97)00160-0