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p70 S6 kinase: an enigma with variations

The S6 ribosomal protein is phosphorylated by p70 S6 kinase (p70 S6k). Although the cellular role of S6 phosphorylation is still not fully clear, studies on p70 S6k and its activation have revealed the existence of a novel signalling pathway, clues to the mechanism of action of certain immunosuppres...

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Bibliographic Details
Published in:Trends in biochemical sciences (Amsterdam. Regular ed.) 1996-05, Vol.21 (5), p.181-185
Main Author: Proud, Christopher G.
Format: Article
Language:English
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Summary:The S6 ribosomal protein is phosphorylated by p70 S6 kinase (p70 S6k). Although the cellular role of S6 phosphorylation is still not fully clear, studies on p70 S6k and its activation have revealed the existence of a novel signalling pathway, clues to the mechanism of action of certain immunosuppressants and insights into the control of gene expression at the levels of transcription and translation.
ISSN:0968-0004
1362-4326
DOI:10.1016/S0968-0004(96)10016-5