Agricultural organophosphate applicators cholinesterase activity and lipoprotein metabolism

The effects of an organophosphorus pesticide, fenitrothion, and fenitrothion combined with fenvalerate on cholinesterase activity were studied. Controls consisted of nonagricultural workers. Among agricultural workers, pesticide applicators, keepers, and loaders experienced depression of cholinester...

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Bibliographic Details
Published in:Bulletin of environmental contamination and toxicology 1991-03, Vol.46 (3), p.351-360
Main Authors: ABIOLA, F. A, HOUETO, P, DIATTA, F, BADIANE, M, FAYOMI, B
Format: Article
Language:English
Subjects:
actividad enzimatica
activite enzymatique
africa
afrique
Agricultural Workers' Diseases - chemically induced
Agricultural Workers' Diseases - enzymology
Agricultural Workers' Diseases - metabolism
Biological and medical sciences
cholinesterase
Cholinesterases - blood
colinesterasa
enzyme inhibitors
enzymic activity
Erythrocytes - enzymology
fenitotrion
fenitrothion
Fenitrothion - adverse effects
fenvalerate
fenvalerato
Humans
inhibidores de enzimas
inhibiteur d' enzyme
Insecticides - adverse effects
lipaemia
lipemia
lipemie
Lipids - blood
lipoproteinas
lipoproteine
lipoproteins
Lipoproteins - blood
Medical sciences
metabolism
metabolisme
metabolismo
obreros
occupational hazards
ouvrier
Pesticides, fertilizers and other agrochemicals toxicology
Protective Clothing
riesgos ocupacionales
risque professionnel
Senegal
Toxicology
workers
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Summary:The effects of an organophosphorus pesticide, fenitrothion, and fenitrothion combined with fenvalerate on cholinesterase activity were studied. Controls consisted of nonagricultural workers. Among agricultural workers, pesticide applicators, keepers, and loaders experienced depression of cholinesterase activity after pesticide exposure under field conditions. Preexposure values did not differ from those of controls. Values for lipids and lipoproteins did not change upon pesticide exposure. Because a variety of application methods and formulations were used, in addition to sampling at varying numbers of days after exposure, it was difficult for the investigators to draw conclusions from the data. It is suggested that some of these variables be controlled for future studies.
ISSN:0007-4861
1432-0800
DOI:10.1007/BF01688931