Recurrent Iritis After Intravenous Administration of Cidofovir

Although iritis is a relatively common side effect with intravitreal injections of cidofovir, this adverse drug reaction rarely occurs with administration of the iv form, and its occurrence has not yet been clearly linked to administration of this drug. We describe a case of recurrent unilateral iri...

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Bibliographic Details
Published in:Clinical infectious diseases 1997-08, Vol.25 (2), p.337-338
Main Authors: Palau, Leonardo A., Tufty, Geoffrey T., Pankey, George A.
Format: Article
Language:English
Subjects:
Adult
Adverse drug reactions
AIDS-Related Opportunistic Infections - drug therapy
Antiviral Agents - administration & dosage
Antiviral Agents - adverse effects
Antiviral Agents - therapeutic use
Biological and medical sciences
Brief Reports
CD4 Lymphocyte Count
Cidofovir
Cytomegalovirus
Cytomegalovirus Retinitis - drug therapy
Cytosine - administration & dosage
Cytosine - adverse effects
Cytosine - analogs & derivatives
Cytosine - therapeutic use
Dosage
Drug toxicity and drugs side effects treatment
Eyes
Humans
Inflammation
Intravenous injections
Iritis
Iritis - chemically induced
Iritis - diagnosis
Male
Medical sciences
Medication administration
Organophosphonates
Organophosphorus Compounds - administration & dosage
Organophosphorus Compounds - adverse effects
Organophosphorus Compounds - therapeutic use
Pharmacology. Drug treatments
Photophobia
Recurrence
Retinitis
Toxicity: eye
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Description
Summary:Although iritis is a relatively common side effect with intravitreal injections of cidofovir, this adverse drug reaction rarely occurs with administration of the iv form, and its occurrence has not yet been clearly linked to administration of this drug. We describe a case of recurrent unilateral iritis following iv administration of cidofovir (Vistide, Gilead Sciences, Foster City, CA) to a patient with AIDS and cytomegalovirus (CMV) retinitis.
ISSN:1058-4838
1537-6591
DOI:10.1086/516916