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Changes in concentrations of glycolysis and krebs cycle metabolites in mosquitofish, Gambusia holbrooki, induced by mercuric chloride and starvation

Starved and fed Gambusia holbrooki were exposed to mercuric chloride (0.62 mg mercury per litre) in 48 h static renewal tests. Metabolites were extracted from samples of caudal tissue for enzyme analysis. Glucose-6-phosphate and fructose-6-phosphate concentrations were decreased by 56-58 and 79 per...

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Bibliographic Details
Published in:Environmental biology of fishes 1992-07, Vol.34 (3), p.315-320
Main Authors: KRAMER, V. J, NEWMAN, M. C, ULTSCH, G. R
Format: Article
Language:English
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Summary:Starved and fed Gambusia holbrooki were exposed to mercuric chloride (0.62 mg mercury per litre) in 48 h static renewal tests. Metabolites were extracted from samples of caudal tissue for enzyme analysis. Glucose-6-phosphate and fructose-6-phosphate concentrations were decreased by 56-58 and 79 per cent respectively in both mercury-exposed and starved, unexposed fish, relative to control fish (fed, unexposed). Mercury-exposed fish also had higher concentrations of pyruvate, alpha-ketoglutarate, succinate and malate. Krebs cycle metabolite concentrations were unaffected by starvation.
ISSN:0378-1909
1573-5133
DOI:10.1007/BF00004779