Evaluation in a clinical setting of the performances of a new rapid confirmatory assay for HIV1/2 serodiagnosis

Highlights • Geenius provides an earlier confirmation of HIV serodiagnosis during acute infection. • Geenius identifies an higher number of p31-negative samples as compared to WB. • Of the p31-negative samples, identified by Geenius, the 44.36% is associated with recent infection as assessed by avid...

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Bibliographic Details
Published in:Journal of clinical virology 2014-09, Vol.61 (1), p.166-169
Main Authors: Abbate, I, Pergola, C, Pisciotta, M, Sciamanna, R, Sias, C, Orchi, N, Libertone, R, Ippolito, G, Capobianchi, M.R
Format: Article
Language:English
Subjects:
Acute infection
Allergy and Immunology
Avidity
Diagnosis
HIV
HIV Infections - diagnosis
HIV-1 - isolation & purification
HIV-2 - isolation & purification
Human immunodeficiency virus 1
Human immunodeficiency virus 2
Humans
Infectious Disease
Retrospective Studies
Rome
Sensitivity and Specificity
Serologic Tests - methods
Time Factors
Western blot
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Summary:Highlights • Geenius provides an earlier confirmation of HIV serodiagnosis during acute infection. • Geenius identifies an higher number of p31-negative samples as compared to WB. • Of the p31-negative samples, identified by Geenius, the 44.36% is associated with recent infection as assessed by avidity test. • Geenius directly discriminates between HIV-1 and -2 infections.
ISSN:1386-6532
1873-5967
DOI:10.1016/j.jcv.2014.06.015